Stem Cell Therapy for Autoimmune Disease

Stem Cell Therapy for Autoimmune Disease

AngličtinaPevná vazba
Burt Richard K.
Taylor & Francis Ltd
EAN: 9781587060311
Skladem u distributora
Předpokládané dodání v pondělí, 20. ledna 2025
5 403 Kč
Běžná cena: 6 003 Kč
Sleva 10 %
ks
Chcete tento titul ještě dnes?
knihkupectví Megabooks Praha Korunní
není dostupné
Librairie Francophone Praha Štěpánská
není dostupné
knihkupectví Megabooks Ostrava
není dostupné
knihkupectví Megabooks Olomouc
není dostupné
knihkupectví Megabooks Plzeň
není dostupné
knihkupectví Megabooks Brno
není dostupné
knihkupectví Megabooks Hradec Králové
není dostupné
knihkupectví Megabooks České Budějovice
není dostupné
knihkupectví Megabooks Liberec
není dostupné

Podrobné informace

Stem cell transplantation may be complicated by treatment-related mortality and like the immune system that it regenerates has equal potential to either create and preserve or destroy. The dual nature that defines stem cells is differentiation that ultimately leads to death and self-renewal, which leads to immortality. What types of stem cells are there? How are they collected? What are their attributes and characteristics? This textbook devotes many chapters to familiarize the reader with the basic science, clinical aspects, and new questions being raised in the field of stem cell biology. Blood stem cells for tolerance and tissue regeneration are a rapidly developing research and clinical field that is being applied to autoimmune diseases. In clinical trials, autologous hematopoietic (blood) stem cells are being used to reduce the cytopenic interval following intense immune suppressive transplant regimens. While as yet not delineated, some possible mechanisms and pathways leading to tolerance after hematopoietic stem cell transplantation are suggested in these chapters. Tissue regeneration from blood stem cells is also suggested by animal experiments on stem cell plasticity or metamoirosis (i.e., change in fate) as described within this textbook. Ongoing early clinical trials on tissue regeneration from blood stem cells are described in the chapter on stem cell therapy for cardiac and peripheral vascular disease. Whether autologous hematopoietic stem cells, through the process of mobilization and reinfusion, may be manipulated to contribute to tissue repair in autoimmune diseases is a future area for translational research.

Hematopoietic stem cells as a therapeutic tool to induce tolerance were first applied to human autoimmune disorders in 1996. Since then, the door has opened on trials involving numerous autoimmune diseases and allogeneic as well as autologous hematopoietic stem cells. Stem cells are becoming a new therapeutic tool to supplement or replace traditional approaches of surgery, pharmacy, and radiotherapy. As the embryonic stem cell-related ethical issues involving creation and destruction are resolved, their clinical application may follow the clinical paths, trails, and trials already being explored with hematopoietic stem cells.

EAN 9781587060311
ISBN 1587060310
Typ produktu Pevná vazba
Vydavatel Taylor & Francis Ltd
Datum vydání 10. května 2004
Stránky 512
Jazyk English
Rozměry 280 x 210
Země United Kingdom
Autoři Burt Richard K.