Multiple Inert Gas Elimination Technique (MIGET)

Multiple Inert Gas Elimination Technique (MIGET)

AngličtinaPevná vazbaTisk na objednávku
Hopkins Susan R.
Springer-Verlag New York Inc.
EAN: 9781493974405
Tisk na objednávku
Předpokládané dodání ve středu, 7. května 2025
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Podrobné informace

The Multiple Inert Gas Elimination Technique (MIGET) is a complex methodology involving specialized gas chromatography and sophisticated mathematics developed in the early 1970’s. Essentially, nobody possesses knowledge of all its elements except for its original developers, and while some practical and theoretical aspects have been published over the years, none have included the level of detail that would be necessary for a potential user to adopt and understand the technique easily. This book is unique in providing a highly detailed, comprehensive technical description of the theory and practice underlying the MIGET to help potential users set up the method and solve problems they may encounter. 

But it is much more than a reference manual – it is a substantial physiological and mathematical treatise in its own right. 

It also has a wide applicability – there is extensive discussion of the common biological problem of quantitative inference. The authors

took measured whole-lung gas exchange variables, and used mathematical procedures to infer the distribution of ventilation and blood flow from this data. In so doing, they developed novel approaches to answer the question: What are the limits to what can be concluded when inferring the inner workings from the “black box” behavior of a system? The book details the approaches developed, which can be generalized to other similar distributed functions within tissues and organs. They involve engineering approaches such as linear and quadratic programming, and uniquely use mathematical tools with biological constraints to obtain as much information as possible about a “black box” system.

 

Lastly, the book summarizes the hundreds of research papers published by a number of groups over the decades in a way never before attempted in order to marshal the world’s literature on the topic and to provide in one place the wealth of important discoveries, both physiological a

nd clinical, enabled by the technique.

 

EAN 9781493974405
ISBN 1493974408
Typ produktu Pevná vazba
Vydavatel Springer-Verlag New York Inc.
Datum vydání 3. prosince 2017
Stránky 329
Jazyk English
Rozměry 235 x 155
Země United States
Sekce Postgraduate, Research & Scholarly
Autoři Hopkins Susan R.; Wagner Peter D.
Ilustrace XIII, 329 p. 56 illus., 24 illus. in color.
Edice 1st ed. 2017
Série Methods in Physiology
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