Distribution of Anti-EBV Antibodies in HIV-1 Positive Individuals

Human Herpes Virus Type 4 or Epstein Barr Virus is known to exert its oncogenic potential in altered immune states, HIV/AIDS being one of them. The HHV4 life cycle involves the continuous production of various latent and lytic proteins. In HIV infection antibodies to non HIV micro-organisms is erratic because the entire immune system is trying to combat the rapidly replicating HIV. HIV associated tumors appear in HIV clinical stage 3. Literature has not been able to demonstrate, in an HIV positive population, the association of HIV clinical staging with EBV antibodies and EBV infection clinical stages . Virologists and clinicians who are interested in the interaction of HIV and other oncogenic viruses will find this a valuable addition to their knowledge.