The Cutaneous Lymphoid Proliferations: A Comprehensive Textbook of Lymphocytic Infiltrates of the Sk

The Cutaneous Lymphoid Proliferations is the go–to reference for a complete, authoritative treatment of the clinical features, phenotype, pathogenesis, histopathology, diagnosis, and treatment of lymphocytic infiltrates of the skin. This second edition incorporates the latest findings from the fields of light microscopy, immunohistochemistry, and flow cytometry and brings readers up to date with the most current thinking in the field. The book starts off with a clinical atlas and introduction to the ontogeny and biology of the lymphoid system. Next, the authors explore novel molecular approaches to the diagnosis of cutaneous lymphoid proliferation and benign lymphocytic infiltrates. The remaining chapters concentrate on major inflammatory skin diseases and lymphoproliferative disorders, including chronic lymphocytic leukemia, lupus, adult T cell leukemia, and primary cutaneous Hodgkin′s disease. The title: – Discusses additional hematologic dyscrasias, including double hit B cell lymphoma, type D lymphomatoid papulosis, myxoid anaplastic large cell lymphoma, and myeloid dendritic cell leukemia – Contains brand new content on paraneoplastic cutaneous manifestations of lymphoproliferative disease, and myelomonocytic dyscrasias, including terminally differentiated histiocytopathies such as Langerhans cell histiocytopathy including Langerhans cell sarcoma and indeterminate cell proliferative disorder – Covers the role of the immune system in the pathogenesis of cutaneous disease – Contains numerous new clinical vignettes that clearly show the application of principles and treatment techniques discussed in the chapter – Discusses the relationships between therapeutic drugs and cutaneous eruptions and carefully notes important drug reactions – Contains hundreds of full–color, high–quality clinical and histologic photographs, with over 100 new A classic reference for unsurpassed coverage of lymphocytic infiltrates of the human skin.