Pharmaceutical Applications of Nano Imine Complexes and their Oxides

The chemistry of imine metal complexes is undergoing rapid development due to their essential roles in biological systems and chemical industries. Moreover, imine ligands which usually contain oxygen and nitrogen donor atoms have played an important role in coordination chemistry. Imines and their complexes have a variety of application including biological, chemical and analytical. Earlier work has shown that some drugs showed increase activity when administrated as metal chalets rather than as organic compounds. Mortality increase caused by infectious diseases is directly related to the bacteria that have multiple resistance to antibiotics. The development of new antibacterial drugs enriched by innovatory and more effective mechanisms of action is clearly an urgent medical need. Fungal infections usually are not only limited to the contamination of surface tissues. Recently, there was a considerable increase in the incidence of systemic fungal infections, which are potentially life-threatening. Exploration and development of more effective antifungal agents is necessity, and the individual imines are considered to be promising antifungal medicines.