Formulation & Development of Floating Drug Delivery System

From above experimental findings it can be concluded that: - Floating tablet of Clopidogrel Bisulphate can be formulated by effervescent technique using combination of different grades of HPMC. - The prepared floating tablets of Clopidogrel Bisulphate showed satisfactory physicochemical properties and floating behaviour. - The mechanism of drug release was found to be matrix diffusion controlled. - Formulations showed satisfactory results from Stability studies. - Further in-vivo investigations are necessary to correlate in-vitro data.